Research trials are designed to be as risk-free as possible, but by their very nature are looking into the unknown. Take the time to read through all research material and ask questions. Participation in clinical trials is a personal choice and may not be for everyone.
Choosing to participate or not to participate is an individual decision that should be respected. Things to Remember When Searching the Web for Research Trials Search for local universities or large rehabilitation centers as both of these institutions tend to run clinical trials. Some websites require user registration prior to a site search. Most sites only require you to register with an e-mail address.
TBI patients will undergo assessments and follow up to determine the healing capacity of cerebral vasculature after TBI. Additionally, the study aims to understand the role of endothelial progenitor cells in the brain after TBI via biospecimen analysis and comparisons to imaging biomarkers.
Both of these alternative strategies are used in standard care. It is unknown if one is more effective than the other. In one strategy doctors concentrate only on preventing high ICP intracranial pressure caused by a swollen brain. All TBIs require immediate assessment by a professional who has experience evaluating head injuries. A neurological exam will judge motor and sensory skills and test hearing and speech, coordination and balance, mental status, and changes in mood or behavior, among other abilities.
Screening tools for coaches and athletic trainers can identify the most concerning concussions for medical evaluation. The ACE is also used to track symptom recovery over time. It also takes into account risk factors including concussion, headache, and psychiatric history that can impact how long it takes to recover from a TBI. Diagnostic imaging. When necessary, medical providers will use brain scans to evaluate the extent of the primary brain injuries and determine if surgery will be needed to help repair any damage to the brain.
Neuropsychological tests to gauge brain functioning are often used in conjunction with imaging in people who have suffered mild TBI.
Such tests involve performing specific cognitive tasks that help assess memory, concentration, information processing, executive functioning, reaction time, and problem solving.
A total score of indicates a severe head injury; indicates moderate injury; and is classified as mild injury. Baseline testing should begin as soon as a child begins a competitive sport. Brain function tests can be repeated at regular intervals every 1 to 2 years and also after a suspected concussion. The results may help health care providers identify any effects from an injury and allow them to make more informed decisions about whether a person is ready to return to their normal activities.
Many factors, including the size, severity, and location of the brain injury, influence how a TBI is treated and how quickly a person might recover. Although brain injury often occurs at the moment of head impact, much of the damage related to severe TBI develops from secondary injuries which happen days or weeks after the initial trauma. For this reason, people who receive immediate medical attention at a certified trauma center tend to have the best health outcomes.
Some people with mild TBI such as concussion may not require treatment other than rest and over-the-counter pain relievers. Children and teens who have a sports-related concussion should stop playing immediately and return to play only after being approved by a concussion injury specialist. Preventing future concussions is critical. While most people recover fully from a first concussion within a few weeks, the rate of recovery from a second or third concussion is generally slower.
Even after symptoms resolve entirely, people should return to their daily activities gradually once they are given permission by a doctor. There is no clear timeline for a safe return to normal activities although there are guidelines such as those from the American Academy of Neurology and the American Medical Society for Sports Medicine to help determine when athletes can return to practice or competition.
Further research is needed to better understand the effects of mild TBI on the brain and to determine when it is safe to resume normal activities. People with a mild TBI should:Make an appointment for a follow-up visit with their healthcare provider to confirm the progress of their recovery. Surgery may be needed to for emergency medical care and to treat secondary damage, including:. People with TBIs may need nutritional supplements to minimize the effects that vitamin, mineral, and other dietary deficiencies may cause over time.
Some individuals may even require tube feeding to maintain the proper balance of nutrients. After the acute care period of in-hospital treatment, people with severe TBI are often transferred to a rehabilitation center where a multidisciplinary team of health care providers help with recovery. The secondary objective of this study is the collection of additional data and specimens from all study subjects that may support other purposes related to the understanding of TBI.
Sorry, in progress, not accepting new patients. One of the most pressing concerns within the VA currently is the provision of interventions that address the cognitive as well as emotional problems faced by Veterans with mild TBI and comorbid conditions. When completed, these studies will inform us whether training core attentional self-regulatory control functions via personally-relevant activities will be effective in improving daily life for Veterans with mild TBI and comorbid conditions.
This project will provide a foundation for future studies to investigate the neural mechanisms that support improvements of cognition and behavior in mTBI. Subjects will be assessed over 3 months. Last updated: December 21, Showing trials for All Female Male. All ages Under 18 Over Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain open to eligible people ages Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment.
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